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    10870892 Compositions for detecting mutant anaplastic lymphoma kinase in lung cancer  
    Novel gene deletions and translocations involving chromosome 2 resulting in fusion proteins combining part of Anaplastic Lymphoma Kinase (ALK) kinase with part of a secondary protein have been...
    10870854 Inhibitory RNA-based therapeutics targeting ANLN for cancer treatment  
    Embodiments of the present disclosure include compositions and methods related to certain siRNA compositions for the treatment of cancer. In specific embodiments, siRNAs are employed for treatment...
    10870702 Methods of assessing and treating cancer in subjects having dysregulated lymphatic systems  
    Provided herein is a method for determining cancer treatment using an immune modulating therapy in a subject in need thereof. The method comprises assessing whether a lymphatic system in a subject...
    10870690 Protein therapeutant and method for treating cancer  
    The present invention relates to compositions for treating cancer by having one or more activities of inhibiting cancer growth, inhibiting cancer cell invasion, and inhibiting cancer recurrence.
    10870657 Compounds for the treatment of cancer and inflammatory disease  
    Provided herein are compounds that inhibit the phosphorylation of MAPK and thus are useful in compositions and methods for treating cancer and inflammatory disease.
    10870647 Imidazopyridine derivative, method for preparing same, and pharmaceutical composition containing same as active ingredient for preventing or treating cancer  
    The present invention relates to a novel imidazopyridine derivative, a method for preparing the same, and a pharmaceutical composition containing the same as an active ingredient for preventing or...
    10870629 18F-labelled compound for prostate cancer diagnosis, and use thereof  
    The present invention relates to an 18F-labelled compound, and a use thereof. The compound selectively binds to a prostate-specific membrane antigen (PSMA), and enables the acquisition of clear...
    10869959 Method and device for treating cancer  
    A method and device treats cancer where blood from a cancer patient passes through an array of passageways within an interior of a chamber. The passageways include wells having porous membrane...
    10869923 Combined cancer therapy with immune checkpoint modulators and fermentation products by symbiotic microbiota  
    Combined therapy of cancer using an immune check point modulators (e.g., an immune checkpoint inhibitor) and a fermented product, which may be prepared using symbiotic microbiota.
    10869897 Peptides and combination of peptides for use in immunotherapy against epithelial ovarian cancer and other cancers  
    The present invention relates to peptides, proteins, nucleic acids and cells for use in immunotherapeutic methods. In particular, the present invention relates to the immunotherapy of cancer. The...
    10869879 Combinations to treat cancer  
    This application describes compounds, compositions, and combinations thereof that can be used to treat cancer, such as cancers with and without BRAF and/or RAS mutations.
    10869869 Method of adjuvant cancer treatment  
    The present invention provides a method of providing adjuvant treatment to a human patient which comprises administering to such a patient therapeutically effective doses of dabrafenib and...
    10869864 Combinations for the treatment of cancer  
    Described herein are combinations comprising a therapeutically effective amount of a first agent and a therapeutically effective amount of a second agent, wherein the first agent is an inhibitor...
    10869863 Multi-arm polymeric targeting anti-cancer conjugate  
    Disclosed is a multi-arm targeting drug conjugate modified by a water-soluble polymer; the drug conjugate has the structural formula of (III). In formula (III), R is an organic core, POLY is a...
    10869855 Method for treating benign prostatic hyperplasia (BPH), prostatitis, and prostate cancer  
    A method for treating benign prostatic hyperplasia (BPH), prostatitis, and/or prostate cancer, including the step of administering an isothiocyanate functional surfactant to a patient affected by...
    10869854 Method for treating skin cancer  
    A method for treating skin cancer including the steps of applying an isothiocyanate functional surfactant to an area affected by skin cancer, wherein the isothiocyanate functional surfactant...
    10866241 Method for the prognosis and treatment of cancer metastasis  
    The present invention relates to a method for the prognosis of bone metastasis in triple negative (including basal-like) breast cancer or, alternatively, ER+ breast cancer (including luminal A and...
    10866240 Method for analyzing PSA and method for distinguishing prostate cancer from prostatic hypertrophy using that method for analyzing PSA  
    A method for distinguishing prostate cancer from prostatic hypertrophy using the method for analyzing PSA and an analysis kit of PSA are provided. An object of the present invention can be solved...
    10865452 Systems and methods for expression-based discrimination of distinct clinical disease states in prostate cancer  
    A system for expression-based discrimination of distinct clinical disease states in prostate cancer is provided that is based on the identification of sets of gene transcripts, which are...
    10865451 Non-invasive blood based monitoring of genomic alterations in cancer  
    The invention provides methods to monitor cell free nucleic acids. The method comprises obtaining a plasma sample from a subject known to have a cancer characterized by a pair of mutually...
    10865415 Prevention, diagnosis and treatment of cancer overexpressing GPR160  
    Provided are a dsRNA construct of an orphan G-protein-coupled receptor GPR160 gene related to prostate cancer and the use thereof, wherein the dsRNA construct of the GPR160 gene and a composition...
    10865388 Method for identifying anti-cancer agents using an in vitro cell culture system that maintains cancer cell stemness  
    An in vitro co-culture system comprising cancer-associated fibroblasts (CAFs) and cancer cells for producing and maintaining cancer stem cells and uses thereof for identifying agents capable of...
    10865250 Anti-cancer fusion polypeptide  
    The disclosure provides a fusion polypeptide specific for both CD137 and HER2/neu, which fusion polypeptide can be useful for directing CD137 clustering and activation to HER2/neu-positive tumor...
    10865232 NKG2D-IG fusion protein for cancer immunotherapy  
    Methods and compositions for cancer immunotherapy are provided. The methods involve the use of a chimeric molecule (e.g., fusion protein) comprising a dimeric NKG2D portion and an Fc portion,...
    10865196 Compounds for treatment of cancer  
    The present invention relates to a compound of formula XXII and a compound of formula 17ya, which are defined as anywhere in the specification, to a composition comprising the same, and to a...
    10864280 Nanodroplet compositions for the efficient delivery of anti-cancer agents  
    Disclosed herein are nanodroplet compositions composed of a copolymer with a hydrophilic block and a hydrophobic block, a poloxamer, an oil, an anti?cancer agent, and optionally a lyoprotectant....
    10864258 Method for treating pancreatic cancer with Toxoplasma gondii vaccine  
    Attenuated Toxoplasma gondii mutants and methods using the same as vaccines in the prevention or treatment pancreatic cancer are provided.
    10864220 Applications of desogestrel in the preparation of anti-colon cancer/breast cancer ER-negative Ah receptor-positive products  
    This invention discloses applications of desogestrel in the preparation of anti-colon cancer/breast cancer ER-negative Ah receptor-positive products. This invention provides applications for...
    10864203 Combination of a PD-1 antagonist and a RAF inhibitor for treating cancer  
    Disclosed herein is a pharmaceutical combination for use in the prevention, delay of progression or treatment of cancer, wherein the pharmaceutical combination exhibits a synergistic efficacy. The...
    10864190 Combination of an antiandrogen with a vitamin K antagonist or with a gamma-glutamyl carboxylase inhibitor for the therapy of androgen receptor positive cancer  
    The present invention relates to the combination of an antiandrogen with a vitamin K antagonist or with a γ-glutamyl carboxylase inhibitor for use in the treatment or prevention of an androgen...
    10864178 Pharmaceutical composition for treatment of cancer containing polyphenol compound as active ingredient  
    The present invention relates to a pharmaceutical composition for treating cancer, containing a polyphenol compound as an active ingredient. The pharmaceutical composition according to the present...
    10864161 Systems and methods for targeted breast cancer therapies  
    Systems and methods for producing liposomes, including control liposomes and immunoliposomes targeting breast cancer are provided. Systems and methods for treating breast cancer, using targeted...
    10864109 Method and system for reducing the likelihood of colorectal cancer in a human being  
    A system and method for reducing the likelihood of colorectal cancer in a human being includes the modification of an individual's gut microbes by employing a Clustered Regularly Interspaced Short...
    10863779 Breast cancer post treatment support garment  
    The invention is related to support garment for breast cancer patients who have undergone or are going through radiation therapy after lumpectomy, mastectomy, or breast reconstruction. This...
    10859577 Method for in vitro diagnosing and prognosing of triple negative breast cancer recurrence  
    The present invention is in the technical field of breast cancer management, and more particularly relates to the diagnosis and/or prognosing of triple-negative breast cancer (TNBC). The invention...
    10858655 Methods and compositions for treating cancer using peptide nucleic acid-based agents  
    The present invention provides compositions and methods for treating cancer with peptide nucleic acid agents. In some embodiments, the present invention provides methods and compositions relating...
    10858626 Adoptive immunotherapy for treating cancer  
    The present invention provides methods for producing and/or expanding tumor-infiltrating lymphocytes (TILs) that can be used in adoptive immunotherapy in cancer treatment.
    10858441 Method of treatment for pancreatic cancer by administering a human-mouse cross-reactive ADAM 17 antibody  
    Pancreatic ductal adenocarcinoma (PDAC) is one of the most lethal types of tumor amongst all human cancers due to late diagnosis and resistant to treatment with chemotherapy and radiation....
    10858438 TRAILR2 CDH17 binding molecules for the treatment of cancer  
    This invention relates to binding molecules that bind specifically to TNF-related apoptosis-inducing ligand receptor 2 (TRAILR2) and cadherin-17 (CDH17) and their use in medicine, pharmaceutical...
    10858429 Methods for treating cancer using an immunotoxin  
    The present invention relates to methods for preventing or treating head and neck spuamous cell cancer and bladder cancer using an immunotoxin comprising (a) a ligand that binds to a protein on...
    10858423 Composition for the treatment of IGF-1R expressing cancer  
    The present invention relates to a method for the treatment of IGF-IR expressing cancers as well as to a compositions and a kit for said traitment. From one aspect, the invention relates to the...
    10858371 Anti-cancer agents and preparation thereof  
    Embodiments provide, among other compounds, a family of compounds that can be used as therapeutic anti-cancer agents, methods for using such compounds to treat cancer, and methods of making such...
    10858349 Compositions and methods for the treatment of cancer  
    The invention relates to the compounds or its pharmaceutical acceptable polymorphs, solvates, enantiomers, stereoisomers and hydrates thereof. The pharmaceutical compositions comprising an...
    10858307 Compositions and methods for treating liver cancer  
    Provided herein are compositions and methods of treating liver cancer by novel anticancer agents.
    10858305 Perillyl alcohol-3-bromopyruvate conjugate and methods of treating cancer  
    NEO218 (3-bromo-2-oxo-propionic acid 4-isopropenyl-cyclohex-1-enylmethyl ester), (see formula 1), is a novel molecule that was generated by covalent fusion of two unrelated agents: 3-bromopyruvate...
    10857245 Diagnostic imaging agent for early bone metastasis from cancer  
    There is provided a diagnostic imaging agent for early bone metastasis from cancer, containing trans-1-amino-[18F]fluorocyclobutanecarboxylic acid or a pharmaceutically acceptable salt thereof as...
    10857244 Methods and compositions for cancer diagnosis  
    The present invention provides reagents and methods for detecting cancer and precancerous lesions in a patient.
    10857230 Co-therapy comprising a small molecule CSF-1R inhibitor and an agonistic antibody that specifically binds CD40 for the treatment of cancer  
    The present invention is directed to methods for treating cancer, preferably a solid tumor or hematological malignancy, including for example pancreatic cancer, lung cancer (including but not...
    10857229 Treatment of ovarian cancer in patients with ascites using a specific binding agent of human angiopoietin-2 in combination with a taxane  
    Methods and compositions for treating ovarian cancer in a human patient with ascites by administering a therapeutically effective amount of an Ang2 inhibitor in combination with a taxane.
    10857225 Smallpox vaccine for cancer treatment  
    Disclosed herein are methods and compositions related to therapy for cancer. More specifically, the disclosed methods and compositions are related to the use of smallpox vaccine to induce an...
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